I've been to 37 countries, and South America is my favorite region. Here are 4 of the best places to visit there.

Chile is an absolute paradise for adventurous travelers, from the north's otherworldly desert to the south's jagged Patagonian peaks.

Many travelers flock to its chic cities along the coast, such as colorful Valparaíso or world-renowned Torres del Paine National Park, famous for its scenic multiday treks.

Yet I'd argue Pucón, a charming city in Chile's Lake District, is the true adventure capital of the country. The lakefront city has incredible white-water rafting, abundant hot springs, and canyoneering opportunities.

Perhaps the most intrepid pursuit, though, is a climb of Pucón's Villarrica volcano — among the most active in all of South America.

Visitors can reach Villarrica's crater on guided day tours, where spurting lava can be visible from above with the naked eye.

Despite its popularity among domestic and Argentine tourists, Brazil's city of Florianópolis still doesn't seem to be on the radar of many North American travelers.

Located on the island of Santa Catarina, Florianópolis is affectionately known as the "Island of Magic" and is home to over 40 beaches.

Each of the island's beaches offers a distinct vibe, from the family-friendly Daniela Beach to the trendy surfing spot Praia Mole.

Its less-populated southern area has some of the island's most remote and stunning beaches, including Lagoinha do Leste, which is only accessible by boat or on foot.

Aside from the beaches, visitors can wander through the Portuguese-influenced town of Santo Antônio de Lisboa, taste fresh oysters at the downtown market, and explore Brazil's nightlife in the hip Lagoa da Conceição neighborhood.

In my opinion, Florianópolis offers the best of Brazil in one package.

Ushuaia, Argentina's southernmost city, is the most common port for cruises to Antarctica. Yet although thousands of cruisers pass through Ushuaia each year, few stay long enough to truly appreciate the region's attractions.

Starting downtown, visitors can find charming, walkable streets lined with outdoor gear shops, cozy cafés, and Argentinean restaurants. Local delicacies, including king crab and Patagonian lamb, are must-tries.

Just over 7 miles from downtown is Tierra del Fuego National Park, with over 20 miles of beautiful hiking trails. Wildlife is abundant in the region, from Fuegian foxes to even penguins at nearby Martillo Island.

Places like Machu Picchu and Cusco may take the top spots on travelers' Peru itineraries, but Arequipa is also worth a visit.

Known as the "White City," Arequipa's colonial-era buildings were constructed with white volcanic stone, making the city's historic center as bright as it is beautiful. Expect Arequipa's Plaza de Armas — the main square — to bustle with activity at any time of day.

Those interested in Andean history should visit the Andean Sanctuaries Museum. The city also provides easy access to Colca Canyon, one of the deepest in the world. It's a popular day trip for tourists in the region.

Arequipa has hundreds of thousands of fewer tourists than Cusco each year, and I've found its rich history, local culture, and beautiful nature are absolutely worth seeing in person.