RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transition

Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08542-2The use of two mouse models of pulmonary fibrosis helped the identification of the transcription factor RUNX2 as a regulator of the transition of alveolar fibroblasts to pathological fibroblasts.

Feb 5, 2025 - 23:19
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RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transition

Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08542-2The use of two mouse models of pulmonary fibrosis helped the identification of the transcription factor RUNX2 as a regulator of the transition of alveolar fibroblasts to pathological fibroblasts.