A neoantigen vaccine generates antitumour immunity in renal cell carcinoma

Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08507-5A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was associated with no recurrence in patients with high-risk clear cell renal cell carcinoma.

Feb 5, 2025 - 17:47
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A neoantigen vaccine generates antitumour immunity in renal cell carcinoma

Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08507-5A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was associated with no recurrence in patients with high-risk clear cell renal cell carcinoma.