Multi-interface licensing of protein import into a phage nucleus

Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08547-xThis study uncovers a highly conserved jumbo phage protein, Imp1, that possesses multiple interfaces to license protein import into a proteinaceous nucleus-like compartment, using a genetic selection that forces the phage to decrease or abolish the import of specific proteins.

Feb 5, 2025 - 17:47
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Multi-interface licensing of protein import into a phage nucleus

Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08547-xThis study uncovers a highly conserved jumbo phage protein, Imp1, that possesses multiple interfaces to license protein import into a proteinaceous nucleus-like compartment, using a genetic selection that forces the phage to decrease or abolish the import of specific proteins.